Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.10/1488
Título: Severe megaloblastic anaemia in an infant
Autor: Rodrigues, V
Dias, A
Brito, MJ
Galvão, I
Ferreira, GC
Palavras-chave: Megaloblastic anaemia
Infant
Breast feeding
Vitamin B(12) deficiency
Data: 2011
Editora: BMJ Pub. Group
Citação: BMJ Case Rep. 2011 May 16;2011. pii: bcr0220113835
Resumo: Vitamin B(12) or cobalamin deficiency, a rare clinical entity in pediatric age, is found most exclusively in breastfed infants, whose mothers are strictly vegetarian non-supplemented or with pernicious anaemia. In this article, the authors describe a 10-month-old infant admitted for vomiting, refusal to eat and prostration. The infant was exclusively breastfed and difficulties in introduction of new foods were reported. Failure to thrive since 5 months of age was also noticed. Laboratory evaluation revealed severe normocytic normochromic anaemia and cobalamin deficit. A diagnosis of α-thalassemia trait was also made. Maternal investigation showed autoimmune pernicious anaemia. This case shows the severity of vitamin B(12) deficiency and the importance of adopting adequate and precocious measures in order to prevent potentially irreversible neurologic damage.
Peer review: yes
URI: http://hdl.handle.net/10400.10/1488
DOI: 10.1136/bcr.02.2011.3835
Versão do Editor: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097362/pdf/bcr.02.2011.3835.pdf
Aparece nas colecções:PED - Artigos

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