Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.10/1511
Título: The effect of NaCl 0.9% and NaCl 0.45% on sodium, chloride, and acid-base balance in a PICU population
Outros títulos: Efeito do NaCl a 0,9% e do NaCl a 0,45% sobre o sódio, cloreto e equilíbrio ácido-base em uma população de UTIP
Autor: Almeida, HI
Mascarenhas, MI
Loureiro, HC
Abadesso, C
Nunes, P
Moniz, M
Machado, MC
Palavras-chave: Acid–base equilibrium
Sodium
Chloride
Child
Pediatric intensive care unit
Data: 2015
Editora: Sociedade Brasileira de Pediatria
Citação: J Pediatr (Rio J). 2015 Jun 10
Resumo: OBJECTIVES:To study the effect of two intravenous maintenance fluids on plasma sodium (Na), and acid-base balance in pediatric intensive care patients during the first 24h of hospitalization. METHODS: A prospective randomized controlled study was performed, which allocated 233 patients to groups: (A) NaCl 0.9% or (B) NaCl 0.45%. Patients were aged 1 day to 18 years, had normal electrolyte concentrations, and suffered an acute insult (medical/surgical). MAIN OUTCOME MEASURED: change in plasma sodium. Parametric tests: t-tests, ANOVA, X2 statistical significance level was set at α=0.05. RESULTS: Group A (n=130): serum Na increased by 2.91 (±3.9)mmol/L at 24h (p<0.01); 2% patients had Na higher than 150mmol/L. Mean urinary Na: 106.6 (±56.8)mmol/L. No change in pH at 0 and 24h. Group B (n=103): serum Na did not display statistically significant changes. Fifteen percent of the patients had Na<135mmol/L at 24h. The two fluids had different effects on respiratory and post-operative situations. CONCLUSIONS: The use of saline 0.9% was associated with a lower incidence of electrolyte disturbances.
Peer review: yes
URI: http://hdl.handle.net/10400.10/1511
DOI: 10.1016/j.jped.2014.12.003
Versão do Editor: http://ac.els-cdn.com/S0021755715000741/1-s2.0-S0021755715000741-main.pdf?_tid=5553f65c-4a69-11e5-912b-00000aacb35d&acdnat=1440425376_57bd755e3b073bf5804dea7ed5041ae5
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