Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.10/990
Título: Tuberculosis diagnosis after bleach processing for early stage tuberculosis laboratory capacity building.
Autor: David, S
Sutre, A
Sanca, A
Mané, A
Henriques, V
Portugal, C
Sancho, L
Cardoso, A
Paixão, E
Duarte, E
Leite, C
Salem, J
Antunes, A
Palavras-chave: Tuberculose
Tuberculosis
Clinical laboratory techniques
Mycobacterium tuberculosis
Data: 2012
Editora: International Union against Tuberculosis and Lung Disease
Citação: Int J Tuberc Lung Dis. 2012 Nov;16(11):1535-7
Resumo: The diagnosis of tuberculosis is seriously hampered in the absence of standard biosafety laboratory facilities for specimen concentration and Mycobacterium tuberculosis culture. Within a laboratory twinning arrangement, heat-fixed direct smear and sediment from 74 bleach-processed and 20 non-processed specimens from Cumura Hospital, Guinea-Bissau, were sent to Lisbon for molecular evaluation of rifampicin resistance. Sequence analysis of a 369 base-pair rpoB locus detected 3.2% (3/94) resistant specimens. To our knowledge, this represents the first report on the molecular analysis of M. tuberculosis from bleach-processed sputum, an alternative to current diagnostic practice in low-resource settings.
Peer review: yes
URI: http://hdl.handle.net/10400.10/990
ISSN: 1027-3719
Aparece nas colecções:PATCLIN - Artigos

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