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Contralateral Upper Limb Weakness Following Botulinum Toxin A Injection for Poststroke Spasticity

dc.contributor.authorCamões-Barbosa, A
dc.contributor.authorRibeiro, I
dc.contributor.authorMedeiros, L
dc.date.accessioned2019-12-05T11:51:05Z
dc.date.available2019-12-05T11:51:05Z
dc.date.issued2019
dc.description.abstractBotulinum toxin type A has been approved for spasticity management in poststroke patients. The adverse effects are generally of two types: those related to local injection; and those related to the systemic effects from spread of the toxin. Contralateral weakness after botulinum toxin A treatment is a rarely reported adverse effect. We report the case of a 33-year-old female who had been receiving regular injections of incobotulinum toxin A due to spasticity of the right limbs after a hemorrhagic stroke. A switch was made to abobotulinum toxin A with an overall conversion ratio of 1:3.83. The patient presented contralateral upper limb paresis, especially of the deltoid muscle, in the second week post-injection. The electroneuromyography showed neuromuscular block due to botulinum toxin A. She recovered completely after eight months. A switch between different formulations of botulinum toxin type A should prompt caution when carrying out unit conversions. Distant side effects may appear, including paresis in the contralateral limbs.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationActa Med Port , 32 (13) 2019 Apr 26[Online ahead of print]pt_PT
dc.identifier.doi10.20344/amp.11503pt_PT
dc.identifier.issn1646-0758
dc.identifier.urihttp://hdl.handle.net/10400.10/2331
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherOrdem dos Médicospt_PT
dc.relation.publisherversionhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/viewFile/11503/5804pt_PT
dc.subjectBotulinum toxins type Apt_PT
dc.subjectMuscle weaknesspt_PT
dc.titleContralateral Upper Limb Weakness Following Botulinum Toxin A Injection for Poststroke Spasticitypt_PT
dc.title.alternativeParesia do Membro Superior Contralateral Após Infiltração de Toxina Botulínica A para Espasticidade Pós-AVCpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceLisboapt_PT
oaire.citation.titleActa Médica Portuguesapt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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