Publication
Baseline ASPECTS and e-ASPECTS Correlation with Infarct Volume and Functional Outcome in Patients Undergoing Mechanical Thrombectomy.
| dc.contributor.author | Olive-Gadea, M | |
| dc.contributor.author | Martins, N | |
| dc.contributor.author | Boned, S | |
| dc.contributor.author | Carvajal, J | |
| dc.contributor.author | Moreno, MJ | |
| dc.contributor.author | Muchada, M | |
| dc.contributor.author | Molina, C | |
| dc.contributor.author | Tomasello, A | |
| dc.contributor.author | Ribo M1, M Rubiera M1. | |
| dc.contributor.author | Rubiera M1., M | |
| dc.date.accessioned | 2018-11-22T16:28:36Z | |
| dc.date.available | 2018-11-22T16:28:36Z | |
| dc.date.issued | 2018 | |
| dc.description.abstract | BACKGROUND AND PURPOSE: The role of Alberta Stroke Program Early CT score (ASPECTS) in predicting which patients are likely to benefit from endovascular therapy (EVT) is not well defined. An automated software (e-ASPECTS) has been created to solve its poor interrater reliability. We aim to evaluate correlation between radiologist (Rx) and e-ASPECTS scoring with cerebral blood volume (CBV) infarct core and with final infarct volume; as well as with long-term functional outcome. METHODS: We included patients with acute ischemic stroke and large vessel occlusion who underwent EVT. We measured baseline radiologist (Rx) ASPECTS and e-ASPECTS, and baseline CBV infarct core on CT perfusion. Final infarct volume was measured on 24-hour control CT. RESULTS: We included 184 patients, in which 82.1% of patients achieved complete recanalization. Median Rx-ASPECTS/e-ASPECTS was 9 (IQR 8-10 vs. IQR 7.75-10) and mean CBV lesion was 29.51 (±47.41) mL. Correlation (rs ) between ASPECTS and e-ASPECTS was .44 (P < .01). Both ASPECTS scores correlated with CBV after 180 minutes of symptom onset (rs = -.41 vs. -.54, P < .01) and with final infarct volume in patients with complete recanalization (rs = -.40 vs. -.43, P < .01). In a logistic regression, either Rx-ASPECTS, e-ASPECTS, and CBV (OR 1.60 vs. 1.87 vs. .96; P < .05) predicted a low infarct volume. Rx-ASPECTS and e-ASPECTS also predicted functional independence (mRS 0-2) at 3 months (1.52 vs. 1.37; P < .05). CONCLUSION: ASPECTS and e-ASPECTS showed a mild correlation with CBV. Rx-ASPECTS, e-ASPECTS, and CBV predicted a low infarct volume after thrombectomy in recanalized patients but only Rx-ASPECTS and e-ASPECTS predicted functional independence at 3 months. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | J Neuroimaging. 2018 Sep 19. | pt_PT |
| dc.identifier.doi | 10.1111/jon.12564. | pt_PT |
| dc.identifier.issn | 1552-6569 | |
| dc.identifier.uri | http://hdl.handle.net/10400.10/2062 | |
| dc.language.iso | eng | pt_PT |
| dc.publisher | American Society of Neuroimaging | pt_PT |
| dc.subject | Stroke | pt_PT |
| dc.subject | Thrombectomy | pt_PT |
| dc.title | Baseline ASPECTS and e-ASPECTS Correlation with Infarct Volume and Functional Outcome in Patients Undergoing Mechanical Thrombectomy. | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Boston | pt_PT |
| oaire.citation.title | Journal of neuroimaging : official journal of the American Society of Neuroimaging. | pt_PT |
| rcaap.rights | closedAccess | pt_PT |
| rcaap.type | article | pt_PT |