Repository logo
 
Publication

Instantaneous wave-free ratio cutoff values for nonculprit stenosis classification in patients with ST-segment elevation myocardial infarction (an iSTEMI substudy).

2020Journal article Restricted access
Simple item page
dc.contributor.authorThim, T
dc.contributor.authorGötberg, M
dc.contributor.authorFröbert, O
dc.contributor.authorNijveldt, R
dc.contributor.authorvan Royen, N
dc.contributor.authorBaptista, SB, et al.
dc.date.accessioned2020-07-06T14:16:33Z
dc.date.available2020-07-06T14:16:33Z
dc.date.issued2020
dc.descriptionAn iSTEMI substudypt_PT
dc.description.abstractOBJECTIVES: The instantaneous wave-free ratio cutoff value of <0.90 for hemodynamic significance of coronary stenoses has been validated in stable patients. We examined different cutoff values in the evaluation of nonculprit stenoses in patients with ST-segment elevation myocardial infarction. METHODS: We measured instantaneous wave-free ratio across nonculprit stenoses in the acute setting and at follow-up in 120 patients with ST-segment elevation myocardial infarction and 157 nonculprit stenoses, of which, 113 patients with 147 nonculprit stenoses completed follow-up. METHODS: The prevalence of nonculprit stenosis hemodynamic significance was 52% in the acute setting and 41% at follow-up. With follow-up, instantaneous wave-free ratio as reference, acute instantaneous wave-free ratio >0.90 had a negative predictive value of 89%. Acute instantaneous wave-free ratio <0.90 had a positive predictive value of 68%. Acute instantaneous wave-free ratio >0.93 had a negative predictive value of 100%. Acute instantaneous wave-free ratio <0.86 and <0.83 had positive predictive values of 71 and 77%. Using acute instantaneous wave-free ratio <0.90 as cutoff for hemodynamic significance yielded the highest degree of classification agreement between acute and follow-up instantaneous wave-free ratio. CONCLUSIONS: In patients with ST-segment elevation myocardial infarction, acute instantaneous wave-free ratio with the cutoff values <0.90 for hemodynamic significance appears optimal in the evaluation of nonculprit stenoses and has a high negative predictive value and a moderate positive predictive value.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCoron Artery Dis. 2020 Aug;31(5):411-416.pt_PT
dc.identifier.doi10.1097/MCA.0000000000000879pt_PT
dc.identifier.issn1473-5830
dc.identifier.urihttp://hdl.handle.net/10400.10/2454
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherLippincott Williams and Wilkinspt_PT
dc.subjectMyocardial infarctionpt_PT
dc.subjectMyocardial fractional flow reservept_PT
dc.titleInstantaneous wave-free ratio cutoff values for nonculprit stenosis classification in patients with ST-segment elevation myocardial infarction (an iSTEMI substudy).pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceLondonpt_PT
oaire.citation.titleCoronary Artery Diseasept_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Coron Artery Dis. 2020.pdf
Size:
252.34 KB
Format:
Adobe Portable Document Format
Download

Collections

CAR - Artigos publicados em revistas indexadas