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HIV and kidney diseases: 35 years of history and consequences.

dc.contributor.authorCampos, P
dc.contributor.authorOrtiz, A
dc.contributor.authorSoto, K
dc.date.accessioned2017-01-11T15:01:39Z
dc.date.available2017-01-11T15:01:39Z
dc.date.issued2016
dc.description.abstractKidney diseases in human immunodeficiency virus (HIV)-infected patients are often misdiagnosed. Despite reductions in morbidity and mortality owing to widespread use of highly effective combination antiretroviral therapy (cART), acute kidney injury (AKI) and chronic kidney disease (CKD) are still more common in these patients than in the general population, and are associated with poor health outcomes. HIV-associated nephropathy and HIV immune complex kidney diseases are the more recognizable HIV-related kidney diseases. However, a broad spectrum of kidney disorders related or not directly related with HIV infection can be observed, including cART-induced AKI, CKD, proximal tubular dysfunction, crystalluria and urolithiasis, among others. This review summarizes the major epidemiologic studies of kidney diseases in HIV-infected patients, discusses novel approaches that may potentially limit nephrotoxicity such as the use of tenofovir alafenamide, and outlines current screening measures for early diagnosis of kidney dysfunction or tubular damage, and for accurate detection of increased risk for acute or chronic kidney diseases.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationClin Kidney J. 2016 Dec;9(6):772-781pt_PT
dc.identifier.doi10.1093/ckj/sfw104pt_PT
dc.identifier.issn2048-8513
dc.identifier.urihttp://hdl.handle.net/10400.10/1788
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherOxford University Presspt_PT
dc.relation.publisherversionhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5162418/pdf/sfw104.pdfpt_PT
dc.subjectKidney diseasespt_PT
dc.subjectHIV infectionspt_PT
dc.subjectDoenças do rimpt_PT
dc.titleHIV and kidney diseases: 35 years of history and consequences.pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceOxfordpt_PT
oaire.citation.endPage781pt_PT
oaire.citation.startPage772pt_PT
oaire.citation.titleClinical kidney journal.pt_PT
oaire.citation.volume9pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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