Publication
Case Report: Pure Red Cell Aplasia due to Angioimmunoblastic T-Cell Lymphoma.
| dc.contributor.author | Vitorino, M | |
| dc.contributor.author | Nunes, F | |
| dc.contributor.author | Costa, M | |
| dc.contributor.author | Porteiro, B | |
| dc.contributor.author | Borges, A | |
| dc.contributor.author | Machado, J | |
| dc.date.accessioned | 2020-07-07T11:58:41Z | |
| dc.date.available | 2020-07-07T11:58:41Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | Pure red cell aplasia (PRCA) is a rare bone marrow failure characterized by a progressive normocytic anemia and reticulocytopenia without leukopenia and thrombocytopenia. It can be associated with various hematological disorders but exceedingly rarely with angioimmunoblastic T-cell lymphoma (AITL). We report the case of a 72-year-old woman with PRCA associated with AITL. The patient presented with severe anemia (hemoglobin 2.6 g/dL) and a low reticulocyte count 0.7%. Direct and indirect Coombs tests were positive. A CT scan of the chest, abdomen, and pelvis revealed multiple lymphadenopathies. A cervical lymph node biopsy was compatible with AITL. A bone marrow biopsy showed medullary involvement by AITL and a severe erythroid hypoplasia with a myeloid:erythroid ratio of 19.70. The patient was started on CHOP and after 6 cycles the PET scan confirmed complete remission | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Case Rep Oncol. 2020 Feb 6;13(1):76-78 | pt_PT |
| dc.identifier.doi | 10.1159/000505533 | pt_PT |
| dc.identifier.issn | 1662-6575 | |
| dc.identifier.uri | http://hdl.handle.net/10400.10/2460 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Karger | pt_PT |
| dc.relation.publisherversion | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036571/pdf/cro-0013-0076.pdf | pt_PT |
| dc.subject | T-cell lymphoma | pt_PT |
| dc.subject | Pure red-cell aplasia | pt_PT |
| dc.subject | Anemia | pt_PT |
| dc.title | Case Report: Pure Red Cell Aplasia due to Angioimmunoblastic T-Cell Lymphoma. | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Basel | pt_PT |
| oaire.citation.title | Case Reports in Oncology | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
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