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Case Report: Pure Red Cell Aplasia due to Angioimmunoblastic T-Cell Lymphoma.

dc.contributor.authorVitorino, M
dc.contributor.authorNunes, F
dc.contributor.authorCosta, M
dc.contributor.authorPorteiro, B
dc.contributor.authorBorges, A
dc.contributor.authorMachado, J
dc.date.accessioned2020-07-07T11:58:41Z
dc.date.available2020-07-07T11:58:41Z
dc.date.issued2020
dc.description.abstractPure red cell aplasia (PRCA) is a rare bone marrow failure characterized by a progressive normocytic anemia and reticulocytopenia without leukopenia and thrombocytopenia. It can be associated with various hematological disorders but exceedingly rarely with angioimmunoblastic T-cell lymphoma (AITL). We report the case of a 72-year-old woman with PRCA associated with AITL. The patient presented with severe anemia (hemoglobin 2.6 g/dL) and a low reticulocyte count 0.7%. Direct and indirect Coombs tests were positive. A CT scan of the chest, abdomen, and pelvis revealed multiple lymphadenopathies. A cervical lymph node biopsy was compatible with AITL. A bone marrow biopsy showed medullary involvement by AITL and a severe erythroid hypoplasia with a myeloid:erythroid ratio of 19.70. The patient was started on CHOP and after 6 cycles the PET scan confirmed complete remissionpt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCase Rep Oncol. 2020 Feb 6;13(1):76-78pt_PT
dc.identifier.doi10.1159/000505533pt_PT
dc.identifier.issn1662-6575
dc.identifier.urihttp://hdl.handle.net/10400.10/2460
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherKargerpt_PT
dc.relation.publisherversionhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036571/pdf/cro-0013-0076.pdfpt_PT
dc.subjectT-cell lymphomapt_PT
dc.subjectPure red-cell aplasiapt_PT
dc.subjectAnemiapt_PT
dc.titleCase Report: Pure Red Cell Aplasia due to Angioimmunoblastic T-Cell Lymphoma.pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceBaselpt_PT
oaire.citation.titleCase Reports in Oncologypt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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