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Endoscopy Timing in Patients with Acute Upper Gastrointestinal Bleeding.

dc.contributor.authorAlexandrino, G
dc.contributor.authorDomingues, D
dc.contributor.authorCarvalho, R
dc.contributor.authorCosta, N
dc.contributor.authorLourenço, C
dc.contributor.authorReis, J
dc.date.accessioned2018-11-20T12:17:55Z
dc.date.available2018-11-20T12:17:55Z
dc.date.issued2018
dc.description.abstractBACKGROUND/AIMS: The role of very early (≤12 hours) endoscopy in nonvariceal upper gastrointestinal bleeding is controversial. We aimed to compare results of very early and early (12-24 hours) endoscopy in patients with upper gastrointestinal bleeding demonstrating low-risk versus high-risk features and nonvariceal versus variceal bleeding. METHODS: : This retrospective study included patients with nonvariceal and variceal upper gastrointestinal bleeding. The primary outcome was a composite of inpatient death, rebleeding, or need for surgery or intensive care unit admission. Endoscopy timing was defined as very early and early. We performed the analysis in two subgroups: (1) high-risk vs. low-risk patients and (2) variceal vs. nonvariceal bleeding. RESULTS: : A total of 102 patients were included, of whom 59.8% underwent urgent endoscopy. Patients who underwent very early endoscopy received endoscopic therapy more frequently (p=0.001), but there was no improvement in other clinical outcomes. Furthermore, patients at low risk and with nonvariceal bleeding who underwent very early endoscopy had a higher risk of the composite outcome. CONCLUSION: s: Very early endoscopy does not seem to be associated with improved clinical outcomes and may lead to poorer outcomes in specific populations with upper gastrointestinal bleeding. The actual benefit of very early endoscopy remains controversial and should be further clarified.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationClin Endosc. 2018 Oct 5 [Epub ahead of print]pt_PT
dc.identifier.doi10.5946/ce.2018.093pt_PT
dc.identifier.issn2234-2443
dc.identifier.urihttp://hdl.handle.net/10400.10/2057
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherKorean Society of Gastrointestinal Endoscopypt_PT
dc.relation.publisherversionhttps://www.e-ce.org/upload/pdf/ce-2018-093.pdfpt_PT
dc.subjectGastrointestinal endoscopypt_PT
dc.subjectGastrointestinal hemorrhagept_PT
dc.subjectEndoscopic hemostasispt_PT
dc.titleEndoscopy Timing in Patients with Acute Upper Gastrointestinal Bleeding.pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceSeoulpt_PT
oaire.citation.titleClinical endoscopypt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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