GIN - Artigos publicados em revistas não indexadas
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Browsing GIN - Artigos publicados em revistas não indexadas by Author "Dias, G"
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- An 18-year-old woman with a 34-cm metaplastic breast carcinomaPublication . Gomes, A; Santos, V; Dias, G; Manso, RT; Gonçalves, L; Coiteiro, M; Gaspar, H; Nazaré, AMetaplastic breast carcinomas (MBCs) are rare malignancies usually with poor prognosis. We report a case of an 18-year-old African female patient who presented with a 34-cm tumor on the right breast. Biopsy showed an extensively necrotic MBC negative for estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 (triple negative). A modified right radical mastectomy was performed, followed by adjuvant chemotherapy. Histology confirmed a widely necrotic undifferentiated malignant tumor, with strong and diffuse expression of vimentin and B-cell lymphoma 2, focal high-molecular-weight keratins and focal CD34 expression; Ki67 was >90%. There was no skin, deep margin or lymph node involvement. Six months after surgery, the patient showed a 9 × 7 cm nodule adjacent to the suture and adherent to the anterior chest wall. The tumor was considered unresectable and the patient evolved with rapid systemic deterioration. The patient had a progression-free survival of 6 months and overall survival of 9 months.
- Anti-NMDA encephalitis and ovarian teratomaPublication . Dias, G; Mendinhos, G; Igreja, F; Pereira, JSAnti-N-methyl-D-aspartate (NMDA) receptor encephalitis may be associated with ovarian teratoma and results in a characteristic syndrome that presents with psychiatric symptoms, rapid decline of the level of consciousness, central hypoventilation and seizures. Immunotherapy and resection of teratoma are effective therapies.
- A case of follicular variant of papillary thyroid carcinoma in a mature cystic teratoma in a young womanPublication . Dias, G; Caeiro, F; Costa, T; Pedro, A; Pereira, JSMalignant transformation of a teratoma occurs in 1-2% of cases, with carcinoma of the thyroid being extremely rare. It is usually diagnosed in the postoperative histopathological exam. We describe a case of thyroid carcinoma in a mature cystic teratoma.