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Browsing by Author "Velez, J"

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  • Dimensões psicopatológicas e comportamentais na infecção VIH
    Publication . Margalho, R; Velez, J; Oliveira, J; Cunha, S; Silvestre, A
    A infecção pelo vírus da imunodeficiência humana adquirida (VIH) tem sido objecto de estudo de diferentes ciências, uma vez que articula realidades biológicas, clínicas e sociais. Desde os tempos do seu aparecimento até à actualidade os avanços no tratamento da infecção VIH têm sido notórios e fascinantes. A terapêutica anti-retrovírica promove uma melhoria na qualidade de vida dos doentes, e aumenta a esperança de vida mas tem associadas dificuldades no plano comportamental, ou seja, na adesão ao tratamento. O objectivo do estudo foi avaliar a influência de determinantes psicopatológicos e comportamentais em doentes seropositivos. Assim, verificámos que o padrão comportamental de risco, em ambos os sexos, é o sexual. Os homens são mais cumpridores que as mulheres em relação ao tratamento, mas são também quem apresenta índices elevados na dimensão hostilidade. Efectivamente, na infecção VIH a percepção de controlo sobre a doença é frustre contribuindo para uma adaptação pautada por sentimentos de incapacidade. Ainda salientamos a vulnerabilidade no feminino, uma vez que as mulheres apresentaram um padrão comportamental de risco significativo
    2008Journal article Open access Show more
  • Non-AIDS-related comorbidities in people living with HIV-1 aged 50 years and older: The AGING POSITIVE study.
    Publication . Serrão, R; Piñero, C; Velez, J; Coutinho, D; Maltez, F; Lino, S; Sarmento, E; Castro, R; Tavares, AP; Pacheco, P; Lopes, MJ; Mansinho, K; Miranda, AC; Neves, I; Abreu, R; Almeida, J; Pássaro, L
    OBJECTIVE: To characterize the profile of non-AIDS-related comorbidities (NARC) in the older HIV-1-infected population and to explore the factors associated with multiple NARC. METHODS: This was a multicentre, cross-sectional study including HIV-1-infected patients aged ≥50 years, who were virologically suppressed and had been on a stable antiretroviral therapy (ART) regimen for at least 6 months. A multiple regression model explored the association between demographic and clinical variables and the number of NARC. RESULTS: Overall, 401 patients were enrolled. The mean age of the patients was 59.3 years and 72.6% were male. The mean duration of HIV-1 infection was 12.0 years and the median exposure to ART was 10.0 years. The mean number of NARC was 2.1, and 34.7% of patients had three or more NARC. Hypercholesterolemia was the most frequent NARC (60.8%), followed by arterial hypertension (39.7%) and chronic depression/anxiety (23.9%). Arterial hypertension and diabetes mellitus were the most frequently treated NARC (95.6% and 92.6% of cases, respectively). The linear regression analysis showed a positive relationship between age and NARC (B=0.032, 95% confidence interval 0.015-0.049; p=0.0003) and between the duration of HIV-1 infection and NARC (B=0.039, 95% confidence interval 0.017-0.059; p=0.0005). CONCLUSIONS: A high prevalence of NARC was found, the most common being metabolic, cardiovascular, and psychological conditions. NARC rates were similar to those reported for the general population, suggesting a larger societal problem beyond HIV infection. A multidisciplinary approach is essential to reduce the burden of complex multi-morbid conditions in the HIV-1-infected population.
    2018Journal article Open access Show more