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An adolescent with sickle cell anaemia experiencing disease-related complications: priapism and leg ulcer--a management challenge.

dc.contributor.authorVasconcelos, A
dc.contributor.authorPrior, AR
dc.contributor.authorFerrão, A
dc.contributor.authorMorais, A
dc.date.accessioned2019-06-07T14:58:54Z
dc.date.available2019-06-07T14:58:54Z
dc.date.issued2012
dc.description.abstractSickle-cell anaemia (SCA) is a multi-system disease, associated with episodes of acute illness and progressive organ damage. Disease severity shows substantial variation and it is often a burden for adolescents. Complications such as leg ulcer and priapism have a significant impact on quality of life. There are still no definitive treatment guidelines available. Considering the embarrassing nature of priapism and the dire consequences for erectile dysfunction, it is important to inform patients, parents and providers about the relationship of SCA to prolonged painful erections. This article will review the pathophysiology and treatment options of SCA focusing the complications of leg ulcers, priapism, cholelithiasis and retinopathy. The case study of a 14-year-old boy is used to present a management challenge of multiple SCA-related complications.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBMJ Case Rep. 2012 Apr 28;2012. pii: bcr1120115146.pt_PT
dc.identifier.doi10.1136/bcr.11.2011.5146pt_PT
dc.identifier.issn1757-790X
dc.identifier.urihttp://hdl.handle.net/10400.10/2289
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMJ Publishing Grouppt_PT
dc.relation.publisherversionhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351650/pdf/bcr.11.2011.5146.pdfpt_PT
dc.subjectAdolescentpt_PT
dc.subjectSickle cell anemiapt_PT
dc.subjectCholelithiasispt_PT
dc.subjectRetinal diseasespt_PT
dc.subjectLeg ulcerpt_PT
dc.titleAn adolescent with sickle cell anaemia experiencing disease-related complications: priapism and leg ulcer--a management challenge.pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceLondonpt_PT
oaire.citation.titleBMJ Case Reportspt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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