Publication
An 18-year-old woman with a 34-cm metaplastic breast carcinoma
| dc.contributor.author | Gomes, A | |
| dc.contributor.author | Santos, V | |
| dc.contributor.author | Dias, G | |
| dc.contributor.author | Manso, RT | |
| dc.contributor.author | Gonçalves, L | |
| dc.contributor.author | Coiteiro, M | |
| dc.contributor.author | Gaspar, H | |
| dc.contributor.author | Nazaré, A | |
| dc.date.accessioned | 2015-04-22T15:22:01Z | |
| dc.date.available | 2015-04-22T15:22:01Z | |
| dc.date.issued | 2015 | |
| dc.description.abstract | Metaplastic breast carcinomas (MBCs) are rare malignancies usually with poor prognosis. We report a case of an 18-year-old African female patient who presented with a 34-cm tumor on the right breast. Biopsy showed an extensively necrotic MBC negative for estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 (triple negative). A modified right radical mastectomy was performed, followed by adjuvant chemotherapy. Histology confirmed a widely necrotic undifferentiated malignant tumor, with strong and diffuse expression of vimentin and B-cell lymphoma 2, focal high-molecular-weight keratins and focal CD34 expression; Ki67 was >90%. There was no skin, deep margin or lymph node involvement. Six months after surgery, the patient showed a 9 × 7 cm nodule adjacent to the suture and adherent to the anterior chest wall. The tumor was considered unresectable and the patient evolved with rapid systemic deterioration. The patient had a progression-free survival of 6 months and overall survival of 9 months. | por |
| dc.identifier.citation | J Surg Case Rep. 2015 Jan;1: 1-4 | por |
| dc.identifier.doi | 10.1093/jscr/rju141. | |
| dc.identifier.uri | http://hdl.handle.net/10400.10/1416 | |
| dc.language.iso | por | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Oxford University Press | por |
| dc.relation.publisherversion | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294453/pdf/rju141.pdf | por |
| dc.subject | Breast neoplasms | por |
| dc.subject | Mastectomy | por |
| dc.subject | Prognosis | por |
| dc.title | An 18-year-old woman with a 34-cm metaplastic breast carcinoma | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Oxford | por |
| oaire.citation.endPage | 4 | por |
| oaire.citation.startPage | 1 | por |
| oaire.citation.title | Journal of surgical case reports | por |
| oaire.citation.volume | 1 | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- Journal of Surgical Case Reports, 2015 , 1–4.pdf
- Size:
- 772.86 KB
- Format:
- Adobe Portable Document Format
License bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- license.txt
- Size:
- 1.71 KB
- Format:
- Item-specific license agreed upon to submission
- Description: