Publication
A Case Report of Nonvasculitic Autoimmune Inflammatory Meningoencephalitis with Sensory Ganglionopathy: A Rare Presentation of Sjögren Syndrome
| dc.contributor.author | Peres, J | |
| dc.contributor.author | Cruz, S | |
| dc.contributor.author | Oliveira, R | |
| dc.contributor.author | Santos, L | |
| dc.contributor.author | Herrero Valverde, A | |
| dc.date.accessioned | 2017-03-06T15:49:55Z | |
| dc.date.available | 2017-03-06T15:49:55Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | A 68-year-old Caucasian female was admitted to the emergency department with a progressive history of behavioural symptoms and anxiety followed by visual and auditory hallucinations, forgetfulness, and impaired gait in the previous 3 months. On examination she was psychotic and had a postural and rest tremor of the upper limbs, cogwheel rigidity of the four limbs, retropulsion on standing position, and inability to walk. During the following 2 weeks she developed xerostomia and unilateral parotiditis that improved with steroids. A simultaneous improvement of the cognitive abilities allowed for the detection of sensory ataxia of the lower limbs. Sensory ganglionopathy was then detected with electrophysiological studies. A diagnosis of Sjögren syndrome was suspected and confirmed by salivary gland scintigraphy, Schirmer's test, and submaxillary gland biopsy. We report a case of Sjögren syndrome associated with central and peripheral nervous system involvement, without sicca symptoms preceding the neurological clinical picture. The coexistence of ganglionopathy and a favourable response to immunosuppression are key features that can lead to the correct diagnosis in cases with atypical CNS symptoms, mimicking a rapidly progressive dementia. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Case Rep Neurol Med. 2017;2017:5696512 | pt_PT |
| dc.identifier.doi | 10.1155/2017/5696512 | pt_PT |
| dc.identifier.issn | 2090-6676 | |
| dc.identifier.uri | http://hdl.handle.net/10400.10/1806 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Hindawi Pub. Corp | pt_PT |
| dc.relation.publisherversion | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5274670/pdf/CRINM2017-5696512.pdf | pt_PT |
| dc.subject | Sjogren's syndrome | pt_PT |
| dc.subject | Síndrome de Sjogren | pt_PT |
| dc.subject | Peripheral nervous system diseases | pt_PT |
| dc.title | A Case Report of Nonvasculitic Autoimmune Inflammatory Meningoencephalitis with Sensory Ganglionopathy: A Rare Presentation of Sjögren Syndrome | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | New York | pt_PT |
| oaire.citation.title | Case Reports in Neurological Medicine | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |