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Hemoglobin A1c in patients on peritoneal dialysis: how should we interpret it?

dc.contributor.authorCoelho, S
dc.contributor.authorRodrigues, A
dc.date.accessioned2016-11-17T11:24:14Z
dc.date.available2016-11-17T11:24:14Z
dc.date.issued2014
dc.description.abstractAlmost half the patients on peritoneal dialysis are diabetic and glycemic control is essential to improve both patient and technique survival. Hemoglobin A1c (HbA1c) is widely used in the general population for diabetes diagnosis and monitoring as it highly correlates with blood glucose levels and outcomes. Its use has been extrapolated to the peritoneal dialysis population, despite HbA1c being commonly underestimated. In renal failure patients, HbA1c is influenced by variables affecting not only glycemia but also hemoglobin and the time of interaction between the two. Importantly, the impact of these variables differs in peritoneal dialysis compared to non-dialysis chronic kidney disease and hemodialysis patients. Although HbA1c in peritoneal dialysis patients is less directly associated with blood glucose levels than in the general population, studies have confirmed its association with patient mortality. In this paper we review the variables that can influence HbA1c value emphasizing their impact in peritoneal dialysis patients. By providing clinicians with a comprehensive understanding of HbA1c results, we provide them with tools for a better patient management care and potential improved outcomes of peritoneal dialysis patients.pt_PT
dc.identifier.citationTher Apher Dial. 2014 Oct;18(5):375-82pt_PT
dc.identifier.doi10.1111/1744-9987.12166pt_PT
dc.identifier.issn1744-9987
dc.identifier.urihttp://hdl.handle.net/10400.10/1751
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWiley-Blackwellpt_PT
dc.subjectDiabetes mellitus type 1pt_PT
dc.subjectDiabetes mellitus type 2pt_PT
dc.subjectChronic renal insufficiencypt_PT
dc.subjectHemoglubinspt_PT
dc.subjectDiabetes mellitus tipo 1pt_PT
dc.subjectDiabetes mellitus tipo 2pt_PT
dc.subjectPeritoneal dialysispt_PT
dc.subjectDiálise peritonealpt_PT
dc.titleHemoglobin A1c in patients on peritoneal dialysis: how should we interpret it?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceCarlton South, Vic., Australiapt_PT
oaire.citation.endPage382pt_PT
oaire.citation.startPage375pt_PT
oaire.citation.titleTherapeutic apheresis and dialysispt_PT
oaire.citation.volume18pt_PT
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT

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