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Vaccines and biologics

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Ann Rheum Dis 2014, 73, 1446–1454.pdf256.72 KBAdobe PDF Download

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Abstract(s)

Patients with autoimmune rheumatic diseases are more susceptible to infectious complications during the course of their disease. The introduction of biologics has been a major achievement in treating these diseases, but an increased risk of infection associated with these therapies has become evident. Some infections can be prevented by vaccination and it is clearly worthwhile considering which immunisations would be sensible and practicable for these patients. To date no formal specific recommendations for patients on biologics have been published. A search was made of Medline (via PubMed) from 1970 to January 2014 to provide results. This review aims to provide a systematic analysis of the data about vaccines and biologics and considers recommendations for vaccination in adult patients with autoimmune rheumatic diseases treated with biologics. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

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Keywords

Autoimmune diseases Rheumatic diseases Biological factors Vaccines

Citation

Ann Rheum Dis. 2014 Aug;73(8):1446-54

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European League Against Rheumatism

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