An OCD patient presenting with a cerebellum venous variant in a family with a strong schizophrenia loading: a case report.

Palma, M; Borja-Santos, N; Trancas, B; Klut, C; Cardoso, G

http://hdl.handle.net/10400.10/1608

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Innov Clin Neurosci. 2012 Sep, 9(9) 18-20.pdf		68.27 KB	Adobe PDF	Download

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Abstract(s)

The role of cerebellar pathology in psychiatric symptoms has long been recognized. Cerebellar pathology has been associated with obsessive-compulsive disorder pathophysiology, particularly with compulsive hoarding. Likewise, some cerebellum abnormalities have been described in schizophrenia, as well as in comorbidity between obsessive-compulsive disorder and schizophrenia. The authors report the case of a 32-year-old woman with obsessive-compulsive disorder and a cerebellum development variant in a family with a strong schizophrenia loading. This case emphasizes the probable role of the cerebellum in the pathophysiology of both obsessive-compulsive disorder and schizophrenia, and reconsiders the existence of a so called schizo-obsessive subtype of schizophrenia.