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High prevalence of ST121 in community-associated methicillin-susceptible Staphylococcus aureus lineages responsible for skin and soft tissue infections in Portuguese children

2011Journal article Open access
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dc.contributor.authorConceição, T
dc.contributor.authorAires-de-Sousa, M
dc.contributor.authorPona, N
dc.contributor.authorBrito, MJ
dc.contributor.authorBarradas, C
dc.contributor.authorCoelho, R
dc.contributor.authorSardinha, T
dc.contributor.authorSancho, L
dc.contributor.authorSousa, JG
dc.contributor.authorMachado, MC
dc.contributor.authorLencastre, H
dc.date.accessioned2011-08-29T11:04:26Z
dc.date.available2011-08-29T11:04:26Z
dc.date.issued2011
dc.description.abstractIn order to evaluate the incidence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in Portugal, we analyzed a collection of 38 S. aureus isolates recovered from 30 children attending the pediatric emergency department of a central hospital in Lisbon due to skin and soft tissue infections. Molecular characterization identified seven clonal lineages among the 35 methicillin-susceptible S. aureus (MSSA) isolates, of which the major lineage PFGE A/t159/ST121 included 63% of the isolates. The three MRSA isolates belonged to the Pediatric clone PFGE D/t535/ST5-IV (n = 2) and to the European CA-MRSA clone PFGE G/t044/ST80-IVc (n = 1). All isolates harbored several virulence factors, namely, leukocidins. Panton-Valentine leukocidin (PVL) was produced by isolates from five MSSA lineages and by the ST80 MRSA. Of interest, this is the first reported isolation of CA-MRSA ST80 in Portugal.por
dc.identifier.citationEur J Clin Microbiol Infect Dis. 2011 Feb;30(2):293-7.por
dc.identifier.issn0934-9723
dc.identifier.urihttp://hdl.handle.net/10400.10/400
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherSpringerpor
dc.subjectCriançapor
dc.subjectInfecções comunitárias adquiridaspor
dc.subjectStaphylococcus aureuspor
dc.subjectInfecções dos tecidos molespor
dc.subjectPortugalpor
dc.subjectSoft tissue infectionspor
dc.titleHigh prevalence of ST121 in community-associated methicillin-susceptible Staphylococcus aureus lineages responsible for skin and soft tissue infections in Portuguese childrenpor
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/EC/FP7/223031
oaire.citation.conferencePlaceBerlinpor
oaire.citation.endPage297por
oaire.citation.startPage293por
oaire.citation.titleEuropean journal of clinical microbiology and infectious diseasespor
oaire.fundingStreamFP7
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameEuropean Commission
rcaap.rightsopenAccesspor
rcaap.typearticlepor
relation.isProjectOfPublicationda143822-6f9c-437b-8e92-c9a7c2c40098
relation.isProjectOfPublication.latestForDiscoveryda143822-6f9c-437b-8e92-c9a7c2c40098

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