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Isolated Visceral Angioedema Induced by Angiotensin-Converting Enzyme Inhibitor
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Orientador(es)
Resumo(s)
Visceral angioedema is a rare complication of therapy with angiotensin-converting
enzyme (ACE) inhibitors. Clinical presentation includes nausea, vomiting, abdominal pain and
diarrhea. Early detection of this entity can prevent recurrent episodes and unnecessary invasive
procedures, including surgery.
This article describes a 46-year-old-woman who presented to the emergency department with
abdominal pain, associated with nausea and vomiting. She had been taking ramipril for 15 days.
A computed tomography was performed which revealed thickening of a jejunal segment, with
submucosal edema.
ACE inhibitor-associated angioedema was suspected and the medication was discontinued, with
resolution of symptoms in 48 h.
After 7 months of follow-up, the patient is asymptomatic.
Despite of its rarity, ACE inhibitor-induced small-bowel angioedema should be included in the
differential diagnosis when patients receiving ACE inhibitor therapy present with abdominal
complaints.
Descrição
Palavras-chave
Angioedema Angiotensin-converting enzyme inhibitors
Contexto Educativo
Citação
GE Port J Gastroenterol. 2016;23(3):162-165
Editora
Sociedade Portuguesa de Gastrenterologia