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The importance of dyspnoea in the diagnosis of chronic obstructive pulmonary disease: a descriptive analysis of a stable cohort in Portugal (SAFE Trial)

dc.contributor.authorBárbara, C
dc.contributor.authorMoita, J
dc.contributor.authorCardoso, J
dc.contributor.authorCosta, R
dc.contributor.authorRedondeiro, R
dc.contributor.authorGaspar, M
dc.date.accessioned2012-08-07T15:53:21Z
dc.date.available2012-08-07T15:53:21Z
dc.date.issued2011
dc.description.abstractINTRODUCTION: The aim of this study was to determine patient-perceived characteristics of chronic obstructive pulmonary disease (COPD) in patients participating in a large trial evaluating tiotropium bromide. PATIENTS AND METHODS: Baseline symptoms were assessed by means of a standardized questionnaire. Patients reported symptoms that led to diagnosis as well as their current most troublesome symptom. RESULTS: Data were obtained from 298 patients, mostly male (95%), with mean (standard deviation) baseline forced expiratory volume in 1 second of 1.1 (0.4) L (40.6 [13.3] % of predicted), mean disease duration of 14.4 (10.1) years and smoking history of 55.1 (25.3) pack-years. Dyspnoea was the most frequently reported symptom leading to COPD diagnosis (55.0% of patients), followed by cough (33.2%). Dyspnoea was also the current most troublesome symptom (82.6%), followed by cough (8.4%). The presence of dyspnoea or cough was independent of COPD severity. The most commonly reported co-morbidities were cardiovascular disorders (49% of patients), gastrointestinal disorders (20%) and metabolic disorders (16%), mainly diabetes mellitus. CONCLUSIONS: This analysis confirms the importance of dyspnoea as the most common symptom leading to initial COPD diagnosis and the symptom most troublesome to patients. Co-morbidities are common among COPD patients, and hence spirometric testing is appropriate in a patient who presents with dyspnoea associated with such a condition.por
dc.identifier.citationRev Port Pneumol. 2011 May-Jun;17(3):131-138por
dc.identifier.issn0873-2159
dc.identifier.urihttp://hdl.handle.net/10400.10/628
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherSociedade Portuguesa de Pneumologiapor
dc.subjectDoença pulmonar obstrutiva crónicapor
dc.subjectDispneiapor
dc.subjectPortugalpor
dc.titleThe importance of dyspnoea in the diagnosis of chronic obstructive pulmonary disease: a descriptive analysis of a stable cohort in Portugal (SAFE Trial)por
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceLisboapor
oaire.citation.endPage138por
oaire.citation.startPage131por
oaire.citation.titleRevista Portuguesa de Pneumologiapor
oaire.citation.volume17por
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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