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Mechanical ventilation in pediatric intensive care units during the season for acute lower respiratory infection: a multicenter study

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dc.contributor.authorFarias, J
dc.contributor.authorFernandez, A
dc.contributor.authorMonteverde, E
dc.contributor.authorFlores, J
dc.contributor.authorBaltodano, A
dc.contributor.authorMenchaca, A
dc.contributor.authorPoterala, R
dc.contributor.authorPanico, F
dc.contributor.authorJohnson, M
dc.contributor.authorvon Dessauer, B
dc.contributor.authorDonoso, A
dc.contributor.authorZavala, I
dc.contributor.authorZavala, C
dc.contributor.authorTroster, E
dc.contributor.authorPeña, Y
dc.contributor.authorFlamenco, C
dc.contributor.authorAlmeida, HI
dc.contributor.authorNilda, V
dc.contributor.authorEsteban, A
dc.contributor.authorLatin-American Group for Mechanical Ventilation in Children
dc.date.accessioned2015-01-29T17:08:40Z
dc.date.available2015-01-29T17:08:40Z
dc.date.issued2012
dc.description.abstractOBJECTIVE: To describe the characteristics and outcomes of mechanical ventilation in pediatric intensive care units during the season of acute lower respiratory infections. DESIGN: Prospective cohort of infants and children receiving mechanical ventilation for at least 12 hrs. SETTING: Sixty medical-surgical pediatric intensive care units. PATIENTS: All consecutive patients admitted to participating pediatric intensive care units during a 28-day period. MEASUREMENTS AND MAIN RESULTS: Of 2,156 patients admitted to pediatric intensive care units, 1185 (55%) received mechanical ventilation for a median of 5 days (interquartile range 2-8). Median age was 7 months (interquartile range 2-25). Main indications for mechanical ventilation were acute respiratory failure in 78% of the patients, altered mental status in 15%, and acute on chronic pulmonary disease in 6%. Median length of stay in the pediatric intensive care units was 10 days (interquartile range 6-18). Overall mortality rate in pediatric intensive care units was 13% (95% confidence interval: 11-15) for the entire population, and 39% (95% confidence interval: 23 - 58) in patients with acute respiratory distress syndrome. Of 1150 attempts at liberation from mechanical ventilation, 62% (95% confidence interval: 60-65) used the spontaneous breathing trial, and 37% (95% confidence interval: 35-40) used gradual reduction of ventilatory support. Noninvasive mechanical ventilation was used initially in 173 patients (15%, 95% confidence interval: 13-17). CONCLUSION: In the season of acute lower respiratory infections, one of every two children admitted to pediatric intensive care units requires mechanical ventilation. Acute respiratory failure was the most common reason for mechanical ventilation. The spontaneous breathing trial was the most commonly used method for liberation from mechanical ventilation.por
dc.identifier.citationPediatr Crit Care Med. 2012 Mar;13(2):158-64por
dc.identifier.doi10.1097/PCC.0b013e3182257b82
dc.identifier.urihttp://hdl.handle.net/10400.10/1351
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherLippincott Williams & Wilkinspor
dc.subjectMechanical ventilationpor
dc.subjectPediatric intensive care unitpor
dc.subjectPortugalpor
dc.subjectVentilação mecânicapor
dc.subjectUnidade de cuidados intensivos pediátricospor
dc.titleMechanical ventilation in pediatric intensive care units during the season for acute lower respiratory infection: a multicenter studypor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceBaltimorepor
oaire.citation.endPage164por
oaire.citation.startPage158por
oaire.citation.titlePediatric Critical Care Medicinepor
oaire.citation.volume13por
rcaap.rightsclosedAccesspor
rcaap.typearticlepor

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