Publication
Incidence of postoperative residual neuromuscular blockade in the postanaesthesia care unit: an observational multicentre study in Portugal.
dc.contributor.author | Esteves, S | |
dc.contributor.author | Martins, M | |
dc.contributor.author | Barros, F | |
dc.contributor.author | Barros, F | |
dc.contributor.author | Canas, M | |
dc.contributor.author | Vitor, P | |
dc.contributor.author | Seabra, M | |
dc.contributor.author | Castro, M | |
dc.contributor.author | Bastardo, I | |
dc.date.accessioned | 2015-08-25T14:28:53Z | |
dc.date.available | 2015-08-25T14:28:53Z | |
dc.date.issued | 2013 | |
dc.description.abstract | CONTEXT: Residual neuromuscular blockade still presents despite the use of intermediate duration muscle relaxants and is a risk factor for postoperative morbidity. OBJECTIVE: To determine the incidence of incomplete postoperative neuromuscular recovery from anaesthesia in a postanaesthesia care unit. DESIGN: Multicentre observational study. SETTING: Public Portuguese hospitals. PATIENTS: Adult patients scheduled for elective surgery requiring general anaesthesia with neuromuscular blocking agents. MAIN OUTCOME MEASURES: An independent anaesthesiologist measured neuromuscular transmission by the TOF-Watch SX acceleromyograph. Train-of-four ratios at least 0.9 and less than 0.9 were assessed as complete and incomplete neuromuscular recovery following general anaesthesia, respectively. RESULTS: The study population consisted of 350 patients [134 men and 216 women, mean (SD) age 54.3 (15.9) years]. Ninety-one patients had a train-of-four ratio less than 0.9 on arrival in the postanaesthesia care unit, an incidence of residual neuromuscular blockade of 26% [95% confidence interval (CI) 21 to 31%]. The most frequent neuromuscular blockers were rocuronium (44.2%) and cisatracurium (32%). A neuromuscular block reversal agent was used in 66.6% of the patients (neostigmine in 97%). The incidence of residual neuromuscular blockade in patients receiving reversal agents was 30% (95% CI 25 to 37%). There were no statistically significant differences in the occurrence of residual blockade relating to the neuromuscular blocker used, although higher percentages were observed for cisatracurium (32.4%) and vecuronium (32%) compared with atracurium (23.6%) and rocuronium (20.8%). Incomplete neuromuscular recovery was significantly more frequent among patients who had received a reversal agent (30.5 vs. 17.1%, P = 0.01). Incomplete neuromuscular recovery was more frequent in patients given propofol than in those exposed to sevoflurane (26.2 vs. 14.3%). CONCLUSION: The incidence of incomplete neuromuscular recovery of 26% confirms that it is relatively frequent in the postoperative period and calls attention to the dimension of this problem in Portugal | por |
dc.identifier.citation | Eur J Anaesthesiol. 2013 May;30(5):243-9 | por |
dc.identifier.doi | 10.1097/EJA.0b013e32835dccd7 | |
dc.identifier.uri | http://hdl.handle.net/10400.10/1517 | |
dc.language.iso | eng | por |
dc.peerreviewed | yes | por |
dc.publisher | European Academy of Anaesthesiology | por |
dc.subject | Neuromuscular blockade | por |
dc.subject | Anesthesia recovery period | por |
dc.subject | Incidence | por |
dc.subject | Portugal | por |
dc.title | Incidence of postoperative residual neuromuscular blockade in the postanaesthesia care unit: an observational multicentre study in Portugal. | por |
dc.type | journal article | |
dspace.entity.type | Publication | |
oaire.citation.conferencePlace | Oxford | por |
oaire.citation.endPage | 249 | por |
oaire.citation.startPage | 243 | por |
oaire.citation.title | European journal of anaesthesiology | por |
oaire.citation.volume | 30 | por |
rcaap.rights | closedAccess | por |
rcaap.type | article | por |
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