Treatment of multidrug-resistant and extensively drug-resistant tuberculosis in adolescent patients

Rodrigues, M; Brito, M; Villar, M; Correia, P

http://hdl.handle.net/10400.10/1343

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Pediatr Infect Dis J. 2014 Jun 33(6) 657-9.pdf		193.23 KB	Adobe PDF	Download

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Abstract(s)

The authors describe 2 pediatric patients with drug-resistant tuberculosis in whom new diagnostic and therapeutic approaches were crucial to good clinical evolution. Although there was good clinical outcome, important side effects with linezolid and amikacin occurred, namely medullary hypoplasia and neurosensorial hypoacusia, respectively. A multidisciplinary approach with close follow up was of major importance in managing these patients.