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Multiple sclerosis and motherhood choice: an observational study in Portuguese women patients.

dc.contributor.authorCarvalho, A
dc.contributor.authorVeiga, A
dc.contributor.authorMorgado, J
dc.contributor.authorTojal, R
dc.contributor.authorRocha, S
dc.contributor.authorVale, J
dc.contributor.authorSa, MJ
dc.contributor.authorTimoteo, A
dc.date.accessioned2016-03-09T16:22:56Z
dc.date.available2016-03-09T16:22:56Z
dc.date.issued2014
dc.description.abstractINTRODUCTION. Multiple sclerosis (MS) is a disabling disease occurring mainly in women of childbearing age. MS may interfere with family planning and motherhood decision. AIM. To study the influence of MS diagnosis and course of the disease on motherhood decision. PATIENTS AND METHODS. The cohort of 35 to 45-year-old female patients diagnosed with MS for at least ten years was selected from six Portuguese MS centers. A structured questionnaire was applied to all patients in consecutive consultation days. Clinical records were reviewed to characterize and collect information about the disease and pregnancies. RESULTS. One hundred women were included; mean age at MS diagnosis was 26.3 ± 5.0 years; 90% of the participants presented with a relapsing-remitting MS; 57% had no pregnancies after the diagnosis. MS type and number of relapses were not significantly different between women with or without pregnancies after the diagnosis (p = 0.39 and p = 0.50, respectively). Seventy-seven percent of the patients did not have the intended number of pregnancies. Main reasons given were fear of future disability and the possibility of having relapses. Forty-three women considered that pregnancy might worsen MS. CONCLUSION. In our population, motherhood choice was unrelated to the MS type and the number of relapses. However, a relevant number of women had fewer pregnancies than those intended before MS diagnosis and believed that pregnancy could worsen the disease. An effort to better inform the patients should be made to minimize the impact of MS diagnosis on motherhood decision.pt_PT
dc.identifier.citationRev Neurol. 2014 Dec 16;59(12):537-42.pt_PT
dc.identifier.issn1576-6578
dc.identifier.urihttp://hdl.handle.net/10400.10/1571
dc.language.isospapt_PT
dc.peerreviewedyespt_PT
dc.publisherViguera Editorespt_PT
dc.subjectMultiple sclerosispt_PT
dc.subjectPregnancy complicationspt_PT
dc.subjectEsclerose múltiplapt_PT
dc.subjectComplicações na gravidezpt_PT
dc.subjectPregnancypt_PT
dc.subjectGravidezpt_PT
dc.subjectPortugalpt_PT
dc.titleMultiple sclerosis and motherhood choice: an observational study in Portuguese women patients.pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceBarcelonapt_PT
oaire.citation.endPage542pt_PT
oaire.citation.startPage537pt_PT
oaire.citation.titleRevista de neurologiapt_PT
oaire.citation.volume59pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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