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TINU syndrome: two clinical cases of tubulo-interstitial nephritis and uveitis

dc.contributor.authorBento, V
dc.contributor.authorCastro, I
dc.contributor.authorBatista, J
dc.contributor.authorMesquita, J
dc.date.accessioned2012-12-28T16:18:34Z
dc.date.available2012-12-28T16:18:34Z
dc.date.issued2008
dc.description.abstractTINU (Tubulo-Interstitial Nephritis and Uveitis) syndrome is a rare disease of unknown aetiology characterised by the association between interstitial nephritis and uveitis. The authors present the cases of two young children whose symptoms began with anorexia and weight loss, associated with renal failure and proteinuria of tubular origin. One child also presented anaemia, glycosuria without hyperglycaemia and microhaematuria. A few months later both developed uveitis. In both cases the renal biopsy showed changes compatible with interstitial nephritis. As interstitial nephritis and uveitis aetiologies were not identified, TINU syndrome was suggested as a possible diagnosis. In both children there was a complete resolution, with one needing systemic steroids and immunosuppressive treatment. TINU syndrome should always be considered in the differential diagnosis of patients with renal and ophthalmologic changes.por
dc.identifier.citationPort J Nephrol Hypert 2008; 22 (3): 263-266por
dc.identifier.issn0872-0169
dc.identifier.urihttp://hdl.handle.net/10400.10/837
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherSociedade Portuguesa de Nefrologiapor
dc.subjectInterstitial nephritispor
dc.subjectTINU syndromepor
dc.subjectUveitispor
dc.titleTINU syndrome: two clinical cases of tubulo-interstitial nephritis and uveitispor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceLisboapor
oaire.citation.endPage266por
oaire.citation.startPage263por
oaire.citation.titlePortuguese Journal of Nephrology and Hypertensionpor
oaire.citation.volume22por
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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