Repository logo

Browsing by Author "Mendinhos, G"

Now showing 1 - 3 of 3
  • Anti-NMDA encephalitis and ovarian teratoma
    Publication . Dias, G; Mendinhos, G; Igreja, F; Pereira, JS
    Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis may be associated with ovarian teratoma and results in a characteristic syndrome that presents with psychiatric symptoms, rapid decline of the level of consciousness, central hypoventilation and seizures. Immunotherapy and resection of teratoma are effective therapies.
    2015Journal article Open access Show more
  • Postpartum hysterectomy: 15-year review
    Publication . Ramilo, I; Caeiro, AF; Mendinhos, G; Santos, AP; Matos, F
    Overview and Aims: Postpartum Hysterectomy (PPH) is considered an obstetrical emergency. Profuse bleeding, the most common indication, may jeopardize the puerperal woman. If not controlled by conservative measures, it may require PPH. Its incidence varies between 0.13 to 5.38 per 1000 births. Women with underlying conditions such as placenta previa, fi- broleiomyomas or previous cesarean section (CS) are at increased risk. We evaluated the incidence of PPH, its indications, risk factors and complications. Material and Methods: Retrospective study of PPH conducted at a tertiary care hospital in 15 years (1997-2011). Results: We found 41 cases of PPH (0.6 per 1000 births). Twenty eight occurred after CS (1.34 /1000) and 13 followed vaginal deliveries (0.27/1000), resulting in an odds ratio of 4.94 (2.56 to 9.54, p < 0.001) for CS vs vaginal delivery. Sixteen patients had a previous uterine surgery (CS and/or curettage) and 8 were nulliparous. The most common indication was uterine atony in 18 cases (43.9 %), followed by unspecified hemorrhage in 8 (19.5 %), placenta accreta in 7 (17.1%) and uterine dehiscence/rupture in 4 (9.8%). In 30 cases it was performed a total hysterectomy, being subtotal in the remaining 11 cases. The main complications were the need for red blood cell transfusion (39), disseminated intravascular coagulation (8) and febrile syndrome (6); 21 postpartum women were admitted in Intensive Care Unit. There were no maternal deaths. Pathologic examination of uterus and placenta showed normal postpartum changes in 11 (26.8 %), placenta accreta in 12 (29.3 %), changes consistent with uterine atony in 8 (19.5 %), fibroleiomyomas in 5 (12.2%) and uterine rupture in 3 (7.3%). Conclusions: hysterectomy remains a required procedure in the treatment of postpartum bleeding resistant to conservative management, being uterine atony the most frequent indication with CS accounting for a five times higher risk than vaginal delivery.
    2015Journal article Open access Show more
  • Tuberculose do aparelho reprodutor feminino: experiência de 10 anos
    Publication . Ramilo, I; Caeiro, F; Mendinhos, G; Santos, AP; Pereira, J
    Introdução: A tuberculose é um problema emergente de saúde pública e uma causa rara de infeção do trato genital feminino. Objectivo: Apresentar os casos de tuberculose genital do nosso serviço, no que se refere à sintomatologia, fatores de risco, modo de apresentação e diagnóstico, intervenção terapêutica, complicações e coexistência de doença sistémica. Material e Métodos: Estudo retrospetivo descritivo compreendendo todos os casos ocorridos durante 10 anos (2002-2011), num hospital de nível II. Resultados: Identificaram-se seis casos de tuberculose genital. A idade média foi de 39 anos com três doentes na pós-menopausa. Um caso estava associado a infeção por VIH. A principal sintomatologia foi a dor pélvica (cinco pacientes), com apenas um caso assintomático. As doentes apresentaram-se com quadros clínicos sugestivos de doença inflamatória pélvica com abcesso tubo-ovárico, suspeita de lesão endometrial, ascite e endometrite pós-parto. Quatro doentes foram submetidas a intervenção cirúrgica. Conclusões: A ocorrência de tuberculose genital feminina é rara na pós-menopausa; no entanto na nossa série, 50% eram pós-menopáusicas. O espectro clínico e a forma de apresentação da tuberculose genital são variáveis, pelo que é necessário um elevado grau de suspeição para o seu diagnóstico, já que pode mimetizar um quadro clínico agudo e condicionar a fertilidade futura.
    2014Journal article Open access Show more