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Publication
Melanoma maligno da mucosa da cabeça e pescoço: casuística do IPO de Lisboa
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Advisor(s)
Abstract(s)
Introdução: O melanoma maligno da mucosa (MMM) é uma
doença rara com mau prognóstico.
Material e Métodos: Estudo retrospetivo de 32 doentes do
Instituto Português de Oncologia Francisco Gentil de Lisboa
com MMM da cabeça e pescoço, no período de 1998 a 2012.
Resultados: Dos 32 casos analisados a idade média foi de 70
anos. O tumor primário localizou-se na cavidade nasal e seios
peri-nasais em 24 doentes e na cavidade oral em 8 casos. A
maioria dos doentes (23) foi submetida a tratamento cirúrgico.
Destes, 16 foram propostos para terapêutica complementar
com Radioterapia. O tempo de seguimento variou de 26 dias a
10 anos. A sobrevida aos 5 anos foi de 18%.
Conclusões: A maioria dos doentes apresentou um estadio
avançado na altura do diagnóstico e, apesar dos tratamentos
instituídos, verificou-se uma elevada mortalidade. O
tratamento de escolha é a cirurgia. O papel da radioterapia
continua a ser controverso.
Introduction: Mucosal melanoma of the head and neck is an uncommon disease with poor prognosis. Material and Methods: Retrospective chart review of 32 patients treated for head and neck mucosal melanoma in a cancer center from 1998 to 2012. Results: There were 32 cases with an average age of 70. The primary tumor was located in the nasal cavity in 24 patients and in the oral cavity in 8 patients. The majority of patients (23) underwent surgical treatment. Of these, 16 were proposed for adjunctive therapy with radiotherapy. Follow-up time ranged between 26 days to 10 years. The five year survival rate was 18%. Conclusions: The majority of patients had an advanced stage at diagnosis and despite the treatments here was a high rate of mortality. The treatment of choice is surgery. The role of radiation therapy remains controversial.
Introduction: Mucosal melanoma of the head and neck is an uncommon disease with poor prognosis. Material and Methods: Retrospective chart review of 32 patients treated for head and neck mucosal melanoma in a cancer center from 1998 to 2012. Results: There were 32 cases with an average age of 70. The primary tumor was located in the nasal cavity in 24 patients and in the oral cavity in 8 patients. The majority of patients (23) underwent surgical treatment. Of these, 16 were proposed for adjunctive therapy with radiotherapy. Follow-up time ranged between 26 days to 10 years. The five year survival rate was 18%. Conclusions: The majority of patients had an advanced stage at diagnosis and despite the treatments here was a high rate of mortality. The treatment of choice is surgery. The role of radiation therapy remains controversial.
Description
Keywords
Neoplasias dos seios perinasais Neoplasias da cabeça e pescoço Melanoma
Citation
Rev Port Otorrinol Cirur Cerv Fac. 2015;53(3):167-171
Publisher
Sociedade Portuguesa de Otorrinolaringologia e Cirurgia Cérvico-Facial