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Comparison of macular thickness and volume in amblyopic children using time domain optical coherence tomography

dc.contributor.authorSilva, F
dc.contributor.authorAlves, S
dc.contributor.authorPina, S
dc.contributor.authorAzevedo, A
dc.contributor.authorPêgo, P
dc.contributor.authorSantos, MJ
dc.contributor.authorJoão, R
dc.date.accessioned2012-12-19T16:17:28Z
dc.date.available2012-12-19T16:17:28Z
dc.date.issued2012
dc.description.abstractPurpose: Cortical and lateral geniculate changes are well documented in amblyopia but retinal involvement is controversial. Our aim was to compare macular volume and thickness between the sound and the amblyopic eye, in children with unilateral amblyopia due to anisometropia or strabismus, using optical coherence tomography. Materials and Methods: Amblyopic children up to the age of 18 were examined with Stratus OCT3, assessing macular volume and thickness. Statistical analysis was done using the Wilcoxon signed rank test and a level of significance of 5% was chosen. Results: 19 amblyopic patients were studied, 15 with strabismus and 4 with anisometropia. The foveal minimum thickness was significantly greater in the amblyopic eye; by contrast, significantly reduced thickness was found in the inner nasal, inner inferior and outer inferior macular areas of the amblyopic eye. Macular volume and retinal thickness in the other macular areas were reduced in amblyopic eyes but this was not significant. Conclusions: There seems to be a difference in macular thickness between both eyes in patients with unilateral amblyopia due to strabismus or anisometropia, at least in some areas. Our results are according to some studies performed so far, although others contradict these results, reflecting the different experimental settings used.por
dc.identifier.citationOftalmologia. 2012 Jul-Set; 36(3) 231-236por
dc.identifier.issn1646-6950
dc.identifier.urihttp://hdl.handle.net/10400.10/817
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherSociedade Portuguesa de Oftalmologiapor
dc.subjectAmblyopiapor
dc.subjectStrabismuspor
dc.subjectAnisometropiapor
dc.subjectOptical coherence tomographypor
dc.titleComparison of macular thickness and volume in amblyopic children using time domain optical coherence tomographypor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceLisboapor
oaire.citation.endPage236por
oaire.citation.startPage231por
oaire.citation.titleOftalmologia: Revista da Sociedade Portuguesa de Oftalmologiapor
oaire.citation.volume36por
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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