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Resumo(s)
Background: Nephrolithiasis has been associated with hypertension, obesity and
diabetes Mellitus. The prevalence of adverse cardiovascular outcomes among kidney
stone formers (KSF) is unknown.
Methods: We examined the IV Portuguese National Health Survey for documenting
possible associations between nephrolithiasis, cardiovascular diseases, diabetes and obesity in the Portuguese adult population.
Results: We obtained 23,349 questionnaires from individuals with ≥ 15 year-old. The
prevalence of kidney stone disease was 7.3%. The prevalence of hypertension was
higher among KSF when compared with the general population (50.4% vs. 30.2%; p
< 0,001). Age and obesity significantly increase the risk for nephrolithiasis. After
adjusting for age and body mass index, KSF have higher prevalence of hypertension
(odds-ratio: 1.841; 95% CI: 1.651 – 2.053), diabetes Mellitus (odds-ratio: 1.475; 95%
CI: 1.283 – 1.696; p < 0.001), myocardial infarction (odds-ratio: 1.338; 95% CI:
1.003 – 1.786; p < 0.05), and stroke (odds-ratio: 1.330; 95% CI: 1.015 – 1.743; p <
0.05) as compared with non-stone formers.
Conclusions: Kidney stone disease is associated with a higher prevalence of chronic diseases and adverse cardiovascular outcomes when compared with the general
population.
Descrição
Palavras-chave
Nefrolitíase Doenças cardiovasculares Obesidade Hipertensão Diabetes mellitus Nephrolithiasis Cardiovascular diseases Hypertension Obesity
Contexto Educativo
Citação
Nephrol Dial Transplant. 2011 Mar;26(3):864-8