Publication
Nephrolithiasis is associated with an increased prevalence of cardiovascular disease
| dc.contributor.author | Domingos, F | |
| dc.contributor.author | Serra, MA | |
| dc.date.accessioned | 2011-10-11T14:27:12Z | |
| dc.date.available | 2011-10-11T14:27:12Z | |
| dc.date.issued | 2011 | |
| dc.description.abstract | Background: Nephrolithiasis has been associated with hypertension, obesity and diabetes Mellitus. The prevalence of adverse cardiovascular outcomes among kidney stone formers (KSF) is unknown. Methods: We examined the IV Portuguese National Health Survey for documenting possible associations between nephrolithiasis, cardiovascular diseases, diabetes and obesity in the Portuguese adult population. Results: We obtained 23,349 questionnaires from individuals with ≥ 15 year-old. The prevalence of kidney stone disease was 7.3%. The prevalence of hypertension was higher among KSF when compared with the general population (50.4% vs. 30.2%; p < 0,001). Age and obesity significantly increase the risk for nephrolithiasis. After adjusting for age and body mass index, KSF have higher prevalence of hypertension (odds-ratio: 1.841; 95% CI: 1.651 – 2.053), diabetes Mellitus (odds-ratio: 1.475; 95% CI: 1.283 – 1.696; p < 0.001), myocardial infarction (odds-ratio: 1.338; 95% CI: 1.003 – 1.786; p < 0.05), and stroke (odds-ratio: 1.330; 95% CI: 1.015 – 1.743; p < 0.05) as compared with non-stone formers. Conclusions: Kidney stone disease is associated with a higher prevalence of chronic diseases and adverse cardiovascular outcomes when compared with the general population. | por |
| dc.identifier.citation | Nephrol Dial Transplant. 2011 Mar;26(3):864-8 | por |
| dc.identifier.issn | 1460-2385 | |
| dc.identifier.uri | http://hdl.handle.net/10400.10/454 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Oxford University Press | por |
| dc.subject | Nefrolitíase | por |
| dc.subject | Doenças cardiovasculares | por |
| dc.subject | Obesidade | por |
| dc.subject | Hipertensão | por |
| dc.subject | Diabetes mellitus | por |
| dc.subject | Nephrolithiasis | por |
| dc.subject | Cardiovascular diseases | por |
| dc.subject | Hypertension | por |
| dc.subject | Obesity | por |
| dc.title | Nephrolithiasis is associated with an increased prevalence of cardiovascular disease | por |
| dc.type | preprint | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Oxford | por |
| oaire.citation.endPage | 868 | por |
| oaire.citation.startPage | 864 | por |
| oaire.citation.title | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association | por |
| rcaap.rights | openAccess | por |
| rcaap.type | preprint | por |
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