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Publication
As doenças psiquiátricas como doenças sistémicas
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Authors
Advisor(s)
Abstract(s)
Introdução: Nos últimos anos, assiste-se a uma
evidência crescente acerca do papel da neuroinflamação
nas doenças psiquiátricas, com uma
inerente evolução conceptual da relação entre
doença psiquiátrica e doença sistémica.
Objectivos: Revisão teórica sobre a relação
entre as doenças psiquiátricas e as doenças
sistémicas.
Métodos: Revisão não sistemática da literatura
através da pesquisa em referências
bibliográficas consideradas relevantes pelo
autor.
Resultados e Conclusões: O papel da neuroinflamação
nas doenças psiquiátricas está
bem documentado nas manifestações psiquiá-
tricas das doenças autoimunes sistémicas, mas
também nalgumas infecções e neoplasias.
Paralelamente, estão presentes anomalias
neuroimunológicas nas doenças psiquiátricas
clássicas, como a depressão, a doença obsessiva-compulsiva,
a doença bipolar e a esquizofrenia.
Background: In the past years, there has been a growing body of evidence regarding the pathogenic role of neuroinflammation in psychiatric illness, with consequent conceptual evolution regarding the relationship between psychiatric illness and systemic disease. Aims: Literature review based on relationship between psychiatric illness and systemic disease. Methods: Nonsystematic literature review based on selected articles and books deemed relevant by the author. Results and Conclusions: The role of neuroinflammation in psychiatric illness is well documented in systemic autoimmune diseases associated with psychiatric manifestations, but also in some infectious diseases and cancer. Parallel to this link, neuroimmunological abnormalities occur in classical psychiatric disorders such as depressive and bipolar disorders, obsessive-compulsive disorder and schizophrenia.
Background: In the past years, there has been a growing body of evidence regarding the pathogenic role of neuroinflammation in psychiatric illness, with consequent conceptual evolution regarding the relationship between psychiatric illness and systemic disease. Aims: Literature review based on relationship between psychiatric illness and systemic disease. Methods: Nonsystematic literature review based on selected articles and books deemed relevant by the author. Results and Conclusions: The role of neuroinflammation in psychiatric illness is well documented in systemic autoimmune diseases associated with psychiatric manifestations, but also in some infectious diseases and cancer. Parallel to this link, neuroimmunological abnormalities occur in classical psychiatric disorders such as depressive and bipolar disorders, obsessive-compulsive disorder and schizophrenia.
Description
Keywords
Doenças auto-imunes Perturbações psicóticas Perturbações mentais Ansiedade Depressão
Citation
Psilogos. 2015; 13(1): 9-15
Publisher
Hospital Prof. Dr. Fernando Fonseca, E.P.E.