Publication
The effect of NaCl 0.9% and NaCl 0.45% on sodium, chloride, and acid-base balance in a PICU population
| dc.contributor.author | Almeida, HI | |
| dc.contributor.author | Mascarenhas, MI | |
| dc.contributor.author | Loureiro, HC | |
| dc.contributor.author | Abadesso, C | |
| dc.contributor.author | Nunes, P | |
| dc.contributor.author | Moniz, M | |
| dc.contributor.author | Machado, MC | |
| dc.date.accessioned | 2015-08-24T14:17:46Z | |
| dc.date.available | 2015-08-24T14:17:46Z | |
| dc.date.issued | 2015 | |
| dc.description.abstract | OBJECTIVES:To study the effect of two intravenous maintenance fluids on plasma sodium (Na), and acid-base balance in pediatric intensive care patients during the first 24h of hospitalization. METHODS: A prospective randomized controlled study was performed, which allocated 233 patients to groups: (A) NaCl 0.9% or (B) NaCl 0.45%. Patients were aged 1 day to 18 years, had normal electrolyte concentrations, and suffered an acute insult (medical/surgical). MAIN OUTCOME MEASURED: change in plasma sodium. Parametric tests: t-tests, ANOVA, X2 statistical significance level was set at α=0.05. RESULTS: Group A (n=130): serum Na increased by 2.91 (±3.9)mmol/L at 24h (p<0.01); 2% patients had Na higher than 150mmol/L. Mean urinary Na: 106.6 (±56.8)mmol/L. No change in pH at 0 and 24h. Group B (n=103): serum Na did not display statistically significant changes. Fifteen percent of the patients had Na<135mmol/L at 24h. The two fluids had different effects on respiratory and post-operative situations. CONCLUSIONS: The use of saline 0.9% was associated with a lower incidence of electrolyte disturbances. | por |
| dc.identifier.citation | J Pediatr (Rio J). 2015 Jun 10 | por |
| dc.identifier.doi | 10.1016/j.jped.2014.12.003 | |
| dc.identifier.uri | http://hdl.handle.net/10400.10/1511 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Sociedade Brasileira de Pediatria | por |
| dc.relation.publisherversion | http://ac.els-cdn.com/S0021755715000741/1-s2.0-S0021755715000741-main.pdf?_tid=5553f65c-4a69-11e5-912b-00000aacb35d&acdnat=1440425376_57bd755e3b073bf5804dea7ed5041ae5 | por |
| dc.subject | Acid–base equilibrium | por |
| dc.subject | Sodium | por |
| dc.subject | Chloride | por |
| dc.subject | Child | por |
| dc.subject | Pediatric intensive care unit | por |
| dc.title | The effect of NaCl 0.9% and NaCl 0.45% on sodium, chloride, and acid-base balance in a PICU population | por |
| dc.title.alternative | Efeito do NaCl a 0,9% e do NaCl a 0,45% sobre o sódio, cloreto e equilíbrio ácido-base em uma população de UTIP | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Rio de Janeiro | por |
| oaire.citation.title | Jornal de Pediatria. | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |