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Accuracy of prenatal culture in predicting intrapartum group B streptococcus colonization status

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OBJECTIVE: To evaluate the positive predictive value (PPV) of group B Streptococcus (GBS) cultures at 35-37 weeks of gestation relative to GBS colonization status at delivery. METHODS: Rectovaginal swabs from 221 women at labor in four Lisbon hospitals were collected for GBS screening according to the CDC guidelines. RESULTS: The PPV was 24.4%. IAP was administered to 100% of prenatally GBS positive women. There was no case of early onset GBS disease (EOD). CONCLUSIONS: Poor accuracy of prenatal cultures in identifying true candidates for IAP highlights the need for Portuguese clinical and laboratory guidelines to prevent EOD and antibiotic overtreatment of pregnant women.

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Pregnancy complications Streptococcal infections Infectious diseases Obstetric labor complications Complicações do trabalho de parto Infecções por estreptocócos

Citation

J Matern Fetal Neonatal Med. 2014 Apr;27(6):640-2

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Informa Healthcare

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